Here are some of the once in a lifetime challenges you can sign up for an incredible sense of achievement - all in the name of a very good cause:
Run the London Marathon - postponed until Sunday 4 October 2020
Visit our appeals page to find out more about current projects we're currently fundraising for.
£5 could buy equipment to give an urgent blood test to stoke patients ahead of clot busting medication.
£10 could help pay for a CD which helps cancer patients relax during treatment.
£17 could buy defibrillator training pads to help teach children how to re-start the heart after a heart attack.
£76 could buy a digital electronic muscle stimulator for children in our spinal unit.
£577 could buy a resuscitator to support a baby's breathing.